Peptide Information

General Information of This Peptide
Peptide ID
BTDP005694
Peptide Name
Beta-theraphotoxin-Eo1a
Symonym
Beta-TRTX-Eo1a
Species
Encyocratella olivacea (Tanzanian black and olive baboon spider)
Uniprot Name
TX621_ENCOL
3D Structure
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2D Sequence
3D Structure
Source
Predict by Alphafold2
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Alphafold Parameters: msa_mode: mmseqs2_uniref_env model_type: auto num_recycles: auto
Sequence
DCRWFLGGCSKDSDCCKHLACRIDGYIKYCAWDGTF
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Sequence Length
36
Mass (Da)
4138
Sequence Removed Signal Peptide
DCRWFLGGCSKDSDCCKHLACRIDGYIKYCAWDGTF
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Disulfide Bond
2-16;9-21;15-30
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Kingdom: Metazoa
Phylum: Arthropoda
Class: Arachnida
Order: Araneae
Family: Theraphosidae
Genus: Encyocratella
Species: Encyocratella olivacea
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Nav1.8 Effective concentration 50
894 nM
 . . [1]
References
Ref 1 The Tarantula Venom Peptide Eo1a Binds to the Domain II S3-S4 Extracellular Loop of Voltage-Gated Sodium Channel Na(V)1.8 to Enhance Activation. Front Pharmacol. 2022 Jan 14;12:789570. doi: 10.3389/fphar.2021.789570. eCollection 2021.
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