Peptide Information

General Information of This Peptide
Peptide ID
BTDP005433
Peptide Name
Alpha-conotoxin PiXXA
Species
Conus princeps (Prince cone)
Uniprot Name
CDKA_CONPG
3D Structure
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2D Sequence
3D Structure
Source
Predict by Alphafold2
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Alphafold Parameters: msa_mode: mmseqs2_uniref_env model_type: auto num_recycles: auto
Sequence
MPKLEMMLLVLLILPLPYFDAAGGQSVHVDGYGDGLARYLQRGERAVKKTCIRSTPGSNW
GRCCLTKMCHTLCCARSDCTCVYRSGKGHGCSCTS
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Sequence Length
95
Mass (Da)
10349
Signal Sequence
MPKLEMMLLVLLILPLPYFDAAGG
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Sequence Removed Signal Peptide
QSVHVDGYGDGLARYLQRGERAVKKTCIRSTPGSNWGRCCLTKMCHTLCCARSDCTCVYR
SGKGHGCSCTS
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        Click to Show/Hide the Complete Species Lineage
Kingdom: Metazoa
Phylum: Mollusca
Class: Gastropoda
Order: Neogastropoda
Family: Conidae
Genus: Conus
Species: Conus princeps
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    nAChR alpha-3-beta-2 Inhibition rate .
6.5 μM
 . [1]
 Target Info    nAChR alpha-7 IC50
6.2 μM
 . . [1]
References
Ref 1 D-Conotoxins in Species of the Eastern Pacific: The Case of Conus princeps from Mexico. Toxins (Basel). 2019 Jul 12;11(7):405. doi: 10.3390/toxins11070405.
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