Peptide Information

General Information of This Peptide
Peptide ID
BTDP005426
Peptide Name
Conotoxin ArchIIIA
Symonym
F27-1
Species
Conus archon (Magistrate cone)
Uniprot Name
CM3A_CONAC
3D Structure
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2D Sequence
3D Structure
Source
Predict by Alphafold2
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Alphafold Parameters: msa_mode: mmseqs2_uniref_env model_type: auto num_recycles: auto
Sequence
CCSALCSRYHCLPCC
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Sequence Length
15
Mass (Da)
1662
Sequence Removed Signal Peptide
CCSALCSRYHCLPCC
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Disulfide Bond
1-15;2-11;6-14
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Kingdom: Metazoa
Phylum: Mollusca
Class: Gastropoda
Order: Neogastropoda
Family: Conidae
Genus: Conus
Species: Conus archon
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    nAChR alpha-7 IC50
45.7 μM
 . . [1]
References
Ref 1 A short framework-III (mini-M-2) conotoxin from the venom of a vermivorous species, Conus archon, inhibits human neuronal nicotinic acetylcholine receptors. Peptides. 2022 Jul;153:170785. doi: 10.1016/j.peptides.2022.170785. Epub 2022 Mar 17.
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