Peptide Information

General Information of This Peptide
Peptide ID
BTDP004943
Peptide Name
RTX-VII
Symonym
Alpha-hexatoxin-MrVII
Species
Macrothele raveni (Funnel-web spider)
Uniprot Name
TXR7_MACRV
Alphafold ID
P0DL75
3D Structure
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2D Sequence
3D Structure
Source
Alphafold db: P0DL75
Sequence
MKTIVYLIVSILLLSSTVLVLAEGNAASHELQEYPIEEQRKCVDGSCDPYSSDAPPCCDN
QICQCIFFVPCYCKYRGK
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Sequence Length
78
Mass (Da)
8712
Signal Sequence
MKTIVYLIVSILLLSSTVLVLA
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Sequence Removed Signal Peptide
EGNAASHELQEYPIEEQRKCVDGSCDPYSSDAPPCCDNQICQCIFFVPCYCKYRGK
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Disulfide Bond
42-58;47-63;57-73;65-71
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Kingdom: Metazoa
Phylum: Arthropoda
Class: Arachnida
Order: Araneae
Family: Macrothelidae
Genus: Macrothele
Species: Macrothele raveni
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Nav1.3 Effective concentration 50
120 nM
 . . [1]
References
Ref 1 Synergetic action of domain II and IV underlies persistent current generation in Nav1.3 as revealed by a tarantula toxin. Sci Rep. 2015 Mar 18;5:9241. doi: 10.1038/srep09241.
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