Peptide Information

General Information of This Peptide
Peptide ID
BTDP004874
Peptide Name
Conantokin R1-A
Symonym
Con R1-A; ConRl-A
Species
Conus rolani (Cone snail)
Uniprot Name
CKR1A_CONRO
Alphafold ID
P0DKY9
3D Structure
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2D Sequence
3D Structure
Source
Alphafold db: P0DKY9
Sequence
MQLYTYLYLLVPLVTFHLILGTGTLDHGGALTERRSTDATALKPEPVLQKSAARSTDDNG
KDRLTQMKRILKKRGNNPRADEEYLKFIEEQRKQGKLDPTKFP
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Sequence Length
103
Mass (Da)
11759
Sequence Removed Signal Peptide
MQLYTYLYLLVPLVTFHLILGTGTLDHGGALTERRSTDATALKPEPVLQKSAARSTDDNG
KDRLTQMKRILKKRGNNPRADEEYLKFIEEQRKQGKLDPTKFP
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Kingdom: Metazoa
Phylum: Mollusca
Class: Gastropoda
Order: Neogastropoda
Family: Conidae
Genus: Conus
Species: Conus rolani
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    NR2B IC50
0.11 μM
 . . [1]
 Target Info    NR2D IC50
0.48 μM
 . . [1]
 Target Info    NR2A IC50
2.1 μM
 . . [1]
 Target Info    NR2C IC50
6.1 μM
 . . [1]
References
Ref 1 Characterization of conantokin Rl-A: molecular phylogeny as structure/function study. J Pept Sci. 2010 Aug;16(8):375-82. doi: 10.1002/psc.1249.
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