Peptide Information

General Information of This Peptide
Peptide ID
BTDP004629
Peptide Name
Potassium channel toxin ImKTx88
Symonym
Potassium channel toxin alpha-KTx
Species
Isometrus maculatus (Lesser brown scorpion) (Scorpio maculatus)
Uniprot Name
KAX_ISOMC
Alphafold ID
P0CJ24
3D Structure
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2D Sequence
3D Structure
Source
Alphafold db: P0CJ24
Sequence
MSNFSVFLIALLFCSVFILSEAQIYTSKECNGSSECYSHCEGITGKRSGKCINKKCYCYR
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Sequence Length
60
Mass (Da)
6763
Sequence Removed Signal Peptide
MSNFSVFLIALLFCSVFILSEAQIYTSKECNGSSECYSHCEGITGKRSGKCINKKCYCYR
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Disulfide Bond
30-51;36-56;40-58
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Kingdom: Metazoa
Phylum: Arthropoda
Class: Arachnida
Order: Scorpiones
Family: Buthidae
Genus: Isometrus
Species: Isometrus maculatus
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Kv1.3 IC50
91 pM
 . . [1]
References
Ref 1 ImKTx88, a novel selective Kv1.3 channel blocker derived from the scorpion Isometrus maculates. Toxicon. 2011 Feb;57(2):348-55. doi: 10.1016/j.toxicon.2010.12.015. Epub 2010 Dec 29.
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