Peptide Information

General Information of This Peptide
Peptide ID
BTDP003906
Peptide Name
Short neurotoxin 1
Symonym
Neurotoxin A
Species
Hydrophis lapemoides (Persian gulf sea snake) (Aturia lapemoides)
Uniprot Name
3S11_HYDLA
Alphafold ID
P01437
3D Structure
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2D Sequence
3D Structure
Source
Alphafold db: P01437
Sequence
MTCCNQQSSQPKTTTNCAESSCYKKTWRDFRGTRIERGCGCPQVKPGIKLECCHTNECNN
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Sequence Length
60
Mass (Da)
6777
Sequence Removed Signal Peptide
MTCCNQQSSQPKTTTNCAESSCYKKTWRDFRGTRIERGCGCPQVKPGIKLECCHTNECNN
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Disulfide Bond
3-22;17-39;41-52;53-58
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Kingdom: Metazoa
Phylum: Chordata
Class: Lepidosauria
Order: Squamata
Family: Hydrophiidae
Genus: Hydrophis
Species: Hydrophis lapemoides
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Kv1.3 Inhibition rate
2.71 %
60 nM
 . [1], [2]
References
Ref 1 Neurotoxins from the venoms of the sea snakes Hydrophis ornatus and Hydrophis lapemoides. Biochem J. 1983 Jul 1;213(1):31-8. doi: 10.1042/bj2130031.
Ref 2 Identification of novel Kv1.3 targeting venom peptides by a single round of autocrine-based selection. Biochem Biophys Res Commun. 2019 Feb 19;509(4):954-959. doi: 10.1016/j.bbrc.2019.01.014. Epub 2019 Jan 14.
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