Peptide Information

General Information of This Peptide
Peptide ID
BTDP003854
Peptide Name
Kunitz-type serine protease inhibitor 1
Symonym
Venom basic protease inhibitor 1; Venom trypsin inhibitor I
Species
Vipera ammodytes ammodytes (Western sand viper)
Uniprot Name
VKT1_VIPAA
Alphafold ID
P00991
3D Structure
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2D Sequence
3D Structure
Source
Alphafold db: P00991
Sequence
MSSGGLLLLLGLLTLWAELTPVSGQDHPKFCYLPADPGRCKAHIPRFYYDSASNKCNKFI
YGGCPGNANNFKTWDECRQTCGASAMGRPT
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Sequence Length
90
Mass (Da)
9831
Signal Sequence
MSSGGLLLLLGLLTLWAELTPVSG
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Sequence Removed Signal Peptide
QDHPKFCYLPADPGRCKAHIPRFYYDSASNKCNKFIYGGCPGNANNFKTWDECRQTCGAS
AMGRPT
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Disulfide Bond
31-81;40-64;56-77
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Kingdom: Metazoa
Phylum: Chordata
Class: Lepidosauria
Order: Squamata
Family: Viperidae
Genus: Vipera
Species: Vipera ammodytes
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    trypsin Inhibition constant
0.34 nM
 . . [1], [2], [3]
References
Ref 1 Adaptive evolution in the snake venom Kunitz/BPTI protein family. FEBS Lett. 2003 Jul 17;547(1-3):131-6. doi: 10.1016/s0014-5793(03)00693-8.
Ref 2 The primary structure of Vipera ammodytes venom trypsin inhibitor I. Biochim Biophys Acta. 1983 Nov 14;748(3):429-35. doi: 10.1016/0167-4838(83)90189-9.
Ref 3 Serine proteinase inhibitors from Vipera ammodytes venom. Isolation and kinetic studies. Eur J Biochem. 1983 Jun 15;133(2):427-32. doi: 10.1111/j.1432-1033.1983.tb07481.x.
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