Peptide Information

General Information of This Peptide
Peptide ID
BTDP003717
Peptide Name
Alpha-conotoxin VxXXIVA
Symonym
AlphaB-conotoxin VxXXIVA
Species
Conus vexillum (Flag cone)
Uniprot Name
CBOA_CONVX
Alphafold ID
J7JU64
3D Structure
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2D Sequence
3D Structure
Source
Alphafold db: J7JU64
Sequence
METLTLLWRASSSCLLVVLSHSLLRLLGVRCLEKSGAQPNKLFRPPCCQKGPSFARHSRC
VYYTQSRE
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Sequence Length
68
Mass (Da)
7724
Sequence Removed Signal Peptide
METLTLLWRASSSCLLVVLSHSLLRLLGVRCLEKSGAQPNKLFRPPCCQKGPSFARHSRC
VYYTQSRE
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Disulfide Bond
31-47;48-60
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Kingdom: Metazoa
Phylum: Mollusca
Class: Gastropoda
Order: Neogastropoda
Family: Conidae
Genus: Conus
Species: Conus vexillum
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    nAChR alpha-9-alpha-10 IC50
1.2 μM
 .
With a disulfide connectivity C1-C2, C3-C4
 [1]
 Target Info    nAChR alpha-9-alpha-10 IC50
3.9 μM
 . . [1]
References
Ref 1 A novel inhibitor of 910 nicotinic acetylcholine receptors from Conus vexillum delineates a new conotoxin superfamily. PLoS One. 2013;8(1):e54648. doi: 10.1371/journal.pone.0054648. Epub 2013 Jan 30.
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