Peptide Information

General Information of This Peptide
Peptide ID
BTDP003615
Peptide Name
Kunitz-type serine protease inhibitor Bi-KTI
Species
Bombus ignitus (Bumblebee)
Uniprot Name
VKT_BOMIG
Alphafold ID
G3LH89
3D Structure
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2D Sequence
3D Structure
Source
Alphafold db: G3LH89
Sequence
MNHKFIALLLVVLCCALAVHQVSAEVPSHCTLSLATGTCKGYFPRFGYNIEMGKCVEFIY
GGCDGNANNFRNLEECQQSCSV
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Sequence Length
82
Mass (Da)
8966
Signal Sequence
MNHKFIALLLVVLCCALAVHQVSA
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Sequence Removed Signal Peptide
EVPSHCTLSLATGTCKGYFPRFGYNIEMGKCVEFIYGGCDGNANNFRNLEECQQSCSV
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Disulfide Bond
30-80;39-63;55-76
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Kingdom: Metazoa
Phylum: Arthropoda
Class: Insecta
Order: Hymenoptera
Family: Apidae
Genus: Bombus
Species: Bombus ignitus
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    plasmin Inhibition constant
3.6 nM
 . . [1]
 Target Info    plasmin IC50
43.53 nM
 . . [1]
References
Ref 1 Antifibrinolytic role of a bee venom serine protease inhibitor that acts as a plasmin inhibitor. PLoS One. 2012;7(2):e32269. doi: 10.1371/journal.pone.0032269. Epub 2012 Feb 16.
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