Peptide Information

General Information of This Peptide
Peptide ID
BTDP003538
Peptide Name
Alpha-conotoxin ViIA
Symonym
ViIA-II
Species
Conus virgo (Virgin cone)
Uniprot Name
CA1A_CONVR
Alphafold ID
F5C0A0
3D Structure
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2D Sequence
3D Structure
Source
Alphafold db: F5C0A0
Sequence
MGMRMMFVVFLLVVFASSVTLDRASYGRYASPVDRASALIAQAILRDCCSNPPCAHNNPD
CR
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Sequence Length
62
Mass (Da)
6810
Signal Sequence
MGMRMMFVVFLLVVFASS
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Sequence Removed Signal Peptide
VTLDRASYGRYASPVDRASALIAQAILRDCCSNPPCAHNNPDCR
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Disulfide Bond
48-54;49-61
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Kingdom: Metazoa
Phylum: Mollusca
Class: Gastropoda
Order: Neogastropoda
Family: Conidae
Genus: Conus
Species: Conus virgo
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    nAChR alpha-3-beta-2 IC50
845.5 nM
 . . [1]
References
Ref 1 A novel 4/6-type alpha-conotoxin ViIA selectively inhibits nAchR 32 subtype. Acta Biochim Biophys Sin (Shanghai). 2015 Dec;47(12):1023-8. doi: 10.1093/abbs/gmv105. Epub 2015 Oct 28.
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