Peptide Information

General Information of This Peptide
Peptide ID
BTDP003476
Peptide Name
AsCystatin
Symonym
AsCys; Cystatin
Species
Austrelaps superbus (Lowland copperhead snake) (Hoplocephalus superbus)
Uniprot Name
CYT_AUSSU
Alphafold ID
E3P6N3
3D Structure
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2D Sequence
3D Structure
Source
Alphafold db: E3P6N3
Sequence
MVHSQLPVAAPLRLLCALLLLPLATMIPGGLSPRSVTDPDVQEAAEFAVQEYNALSANAY
YYKQLRIVEAQSQVVTGAKYYLTMELMKTKCAKTTGKPKVYKEIQNCELPPKAQQEKLTC
RFQVWSCPWLQKIELTKMSCN
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Sequence Length
141
Mass (Da)
15855
Signal Sequence
MVHSQLPVAAPLRLLCALLLLPLATM
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Sequence Removed Signal Peptide
IPGGLSPRSVTDPDVQEAAEFAVQEYNALSANAYYYKQLRIVEAQSQVVTGAKYYLTMEL
MKTKCAKTTGKPKVYKEIQNCELPPKAQQEKLTCRFQVWSCPWLQKIELTKMSCN
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Disulfide Bond
91-107;120-140
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Kingdom: Metazoa
Phylum: Chordata
Class: Lepidosauria
Order: Squamata
Family: Elapidae
Genus: Austrelaps
Species: Austrelaps superbus
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    cathepsin L Inhibition constant
0.89 pM
 . . [1]
 Target Info    papain Inhibition constant
1.74 pM
 . . [1]
 Target Info    cathepsin B Inhibition constant
0.69 nM
 . . [1]
References
Ref 1 Cloning and characterisation of novel cystatins from elapid snake venom glands. Biochimie. 2011 Apr;93(4):659-68. doi: 10.1016/j.biochi.2010.12.008. Epub 2010 Dec 21.
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