Peptide Information

General Information of This Peptide
Peptide ID
BTDP002892
Peptide Name
Kunitz-type serine protease inhibitor bicolin
Species
Vespa bicolor (Black shield wasp)
Uniprot Name
VKT_VESBI
Alphafold ID
C0LNR2
3D Structure
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2D Sequence
3D Structure
Source
Alphafold db: C0LNR2
Sequence
MNAKILALLIGVVFVGLFTVSTPAHPLCLLDPPFGFCQSSISRFAPVVGKCREYIYGGCS
GKANNFQAQAKCQANCG
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Sequence Length
77
Mass (Da)
8141
Signal Sequence
MNAKILALLIGVVFVGLFTVSTPAHP
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Sequence Removed Signal Peptide
LCLLDPPFGFCQSSISRFAPVVGKCREYIYGGCSGKANNFQAQAKCQANCG
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Disulfide Bond
28-76;37-59;51-72
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Kingdom: Metazoa
Phylum: Arthropoda
Class: Insecta
Order: Hymenoptera
Family: Vespidae
Genus: Vespa
Species: Vespa bicolor
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    trypsin Inhibition constant
550 nM
 . . [1]
 Target Info    thrombin Inhibition constant
26 μM
 . . [1]
References
Ref 1 A novel serine protease inhibitor from the venom of Vespa bicolor Fabricius. Comp Biochem Physiol B Biochem Mol Biol. 2009 May;153(1):116-20. doi: 10.1016/j.cbpb.2009.02.010. Epub 2009 Mar 1.
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