Peptide Information

General Information of This Peptide
Peptide ID
BTDP002695
Peptide Name
Pi-stichotoxin-Hmg5a
Symonym
Pi-AnmTX Hmg 1b-5
Species
Heteractis magnifica (Magnificent sea anemone) (Radianthus magnifica)
Uniprot Name
5API_HETMG
3D Structure
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2D Sequence
3D Structure
Source
Predict by Alphafold2
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Alphafold Parameters: msa_mode: mmseqs2_uniref_env model_type: auto num_recycles: auto
Sequence
MDYQRLLFLFAVAMVITTTVALPQDTALMDGNGTGQLQKRGTPCKCLGYTGVYWFMITRC
PNGHGYNLSCPYFLGVCCVKK
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Sequence Length
81
Mass (Da)
8993
Signal Sequence
MDYQRLLFLFAVAMVITTTVA
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Sequence Removed Signal Peptide
LPQDTALMDGNGTGQLQKRGTPCKCLGYTGVYWFMITRCPNGHGYNLSCPYFLGVCCVKK
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Disulfide Bond
44-77;46-70;60-78
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Kingdom: Metazoa
Phylum: Cnidaria
Class: Anthozoa
Order: Actiniaria
Family: Stichodactylidae
Genus: Heteractis
Species: Heteractis magnifica
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    ASIC3 IC50
13.8 μM
 . . [1]
References
Ref 1 Nicotinic Acetylcholine Receptors Are Novel Targets of APETx-like Toxins from the Sea Anemone Heteractis magnifica. Toxins (Basel). 2022 Oct 11;14(10):697. doi: 10.3390/toxins14100697.
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