Peptide Information

General Information of This Peptide
Peptide ID
BTDP001755
Peptide Name
PI-stichotoxin-Hcr2k
Symonym
Kunitz-peptide HCIQ1c9
Species
Heteractis crispa (Leathery sea anemone) (Radianthus macrodactylus)
Uniprot Name
VKT2K_HETCR
Alphafold ID
A0A6B7FEJ3
3D Structure
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2D Sequence
3D Structure
Source
Alphafold db: A0A6B7FEJ3
Sequence
GFYFRSIQGFYFKRIQGNICSEPKKVGRCRRSFPRFYFDSETGKCTPFIYGGCGGNGNNF
ETLHACRAICRA
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Sequence Length
72
Mass (Da)
8233
Sequence Removed Signal Peptide
GFYFRSIQGFYFKRIQGNICSEPKKVGRCRRSFPRFYFDSETGKCTPFIYGGCGGNGNNF
ETLHACRAICRA
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Disulfide Bond
20-70;29-53;45-66
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Kingdom: Metazoa
Phylum: Cnidaria
Class: Anthozoa
Order: Actiniaria
Family: Stichodactylidae
Genus: Radianthus
Species: Radianthus crispa
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    serine protease trypsin Inhibition constant
630 nM
 . . [1]
References
Ref 1 Kunitz-Type Peptides from Sea Anemones Protect Neuronal Cells against Parkinson's Disease Inductors via Inhibition of ROS Production and ATP-Induced P2X7 Receptor Activation. Int J Mol Sci. 2022 May 4;23(9):5115. doi: 10.3390/ijms23095115.
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