Peptide Information

General Information of This Peptide
Peptide ID
BTDP001663
Peptide Name
O-conotoxin GeXXXIA
Symonym
O-conotoxin GeXXVIIA
Species
Conus generalis (General cone)
Uniprot Name
O1VA_CONGR
Alphafold ID
A0A2I4QAG8
3D Structure
Download
2D Sequence
3D Structure
Source
Alphafold db: A0A2I4QAG8
Sequence
MKLTCVLIITVLFLTACQLTTAVTYSRGEHKHRALMSTGTNYRLLKTCRGSGRYCRSPYD
CRRRYCRRISDACV
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Sequence Length
74
Mass (Da)
8540
Signal Sequence
MKLTCVLIITVLFLTACQLTTA
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Sequence Removed Signal Peptide
VTYSRGEHKHRALMSTGTNYRLLKTCRGSGRYCRSPYDCRRRYCRRISDACV
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        Click to Show/Hide the Complete Species Lineage
Kingdom: Metazoa
Phylum: Mollusca
Class: Gastropoda
Order: Neogastropoda
Family: Conidae
Genus: Conus
Species: Conus generalis
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    nAChR alpha-9-alpha-10 IC50
16.2 nM
 . . [1]
References
Ref 1 Identification of a Novel O-Conotoxin Reveals an Unusual and Potent Inhibitor of the Human 910 Nicotinic Acetylcholine Receptor. Mar Drugs. 2017 Jun 9;15(6):170. doi: 10.3390/md15060170.
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