Peptide Information

General Information of This Peptide
Peptide ID
BTDP001506
Peptide Name
u-conotoxin TsIIIA
Species
Conus rolani (Cone snail)
3D Structure
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2D Sequence
3D Structure
Source
Predict by Alphafold2
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Alphafold Parameters: msa_mode: mmseqs2_uniref_env model_type: auto num_recycles: auto
Sequence
GCCRWPCPSRCGMARCCSS
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Sequence Length
19
Mass (Da)
2063
Sequence Removed Signal Peptide
GCCRWPCPSRCGMARCCSS
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Disulfide Bond
2-11;3-16;7-17
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Kingdom: Metazoa
Phylum: Mollusca
Class: Gastropoda
Order: Neogastropoda
Family: Conidae
Genus: Conus
Species: Conus rolani
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Nav1.8 IC50
2.11 μM
 . . [1]
References
Ref 1 -conotoxin TsIIIA, a peptide inhibitor of human voltage-gated sodium channel hNa(v)1.8. Toxicon. 2020 Oct 30;186:29-34. doi: 10.1016/j.toxicon.2020.07.024. Epub 2020 Aug 3.
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