Peptide Information

General Information of This Peptide
Peptide ID
BTDP001092
Peptide Name
Neurotoxin HsTX1 (R14[Abu])
Symonym
Neurotoxin HsTX1 (R14[Abu])
3D Structure
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2D Sequence
3D Structure
Source
Predict by Alphafold2
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Alphafold Parameters: msa_mode: mmseqs2_uniref_env model_type: auto num_recycles: auto
Original Sequence
ASCRTPKDCADPCRKETGCPYGKCMNRKCKCNRC
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Mutant Sequence
ASCRTPKDCADPC[Abu]KETGCPYGKCMNRKCKCNRC
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Sequence Length
34
Mass(Da)
3747
Sequence Removed Signal Peptide
ASCRTPKDCADPC[Abu]KETGCPYGKCMNRKCKCNRC
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Disulfide Bond
3-24;9-29;13-31;19-34
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N.A.
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Kv1.1 Inhibition rate .
100 nM
Blocker
 [1]
 Target Info    Kv1.3 IC50
0.05 nM
 .
Blocker
 [1]
References
Ref 1 A potent and Kv1.3-selective analogue of the scorpion toxin HsTX1 as a potential therapeutic for autoimmune diseases. Sci Rep. 2014 Mar 28;4:4509. doi: 10.1038/srep04509.
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