Peptide Information

General Information of This Peptide
Peptide ID
BTDP001090
Peptide Name
Neurotoxin HsTX1 (A14R,C19[Abu],C34[Abu])
Symonym
Neurotoxin HsTX1 (A14R,C19[Abu],C34[Abu])
3D Structure
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2D Sequence
3D Structure
Source
Predict by Alphafold2
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Alphafold Parameters: msa_mode: mmseqs2_uniref_env model_type: auto num_recycles: auto
Original Sequence
ASCRTPKDCADPCRKETGCPYGKCMNRKCKCNRC
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Mutant Sequence
ASCRTPKDCADPCRKETG[Abu]PYGKCMNRKCKCNR[Abu]
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Sequence Length
34
Mass(Da)
3784
Sequence Removed Signal Peptide
ASCRTPKDCADPCRKETG[Abu]PYGKCMNRKCKCNR[Abu]
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Disulfide Bond
3-24;9-29;13-31;19-34
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N.A.
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Kv1.4 Inhibition rate .
100 nM
Blocker
 [1]
 Target Info    Kv1.5 Inhibition rate .
100 nM
Blocker
 [1]
References
Ref 1 The impact of the fourth disulfide bridge in scorpion toxins of the alpha-KTx6 subfamily. Proteins. 2005 Dec 1;61(4):1010-23. doi: 10.1002/prot.20681.
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