Peptide Information

General Information of This Peptide
Peptide ID
BTDP001002
Peptide Name
ScyTx (R6K)
Symonym
ScyTx (R6K)
3D Structure
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2D Sequence
3D Structure
Source
Predict by Alphafold2
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Alphafold Parameters: msa_mode: mmseqs2_uniref_env model_type: auto num_recycles: auto
Original Sequence
AFCNLRMCQLSCRSLGLLGKCIGDKCECVKH
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Mutant Sequence
AFCNLKMCQLSCRSLGLLGKCIGDKCECVKH
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Sequence Length
31
Mass(Da)
3395
Sequence Removed Signal Peptide
AFCNLKMCQLSCRSLGLLGKCIGDKCECVKH
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N.A.
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    KCa2.2 Dissociation constant
4.5 nM
 .
Blocker
 [1]
 Target Info    KCa2.3 Dissociation constant
36 nM
 .
Blocker
 [1]
References
Ref 1 Design and characterization of a highly selective peptide inhibitor of the small conductance calcium-activated K+ channel, SkCa2. J Biol Chem. 2001 Nov 16;276(46):43145-51. doi: 10.1074/jbc.M106981200. Epub 2001 Aug 29.
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