Peptide Information

General Information of This Peptide
Peptide ID
BTDP000931
Peptide Name
Toxin MeKTx13-3 (K15A)
Symonym
Toxin MeKTx13-3 (K15A)
3D Structure
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2D Sequence
3D Structure
Source
Predict by Alphafold2
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Alphafold Parameters: msa_mode: mmseqs2_uniref_env model_type: auto num_recycles: auto
Original Sequence
VGINVKCKHSGQCLKPCKDAGMRFGKCINGKCDCTPK
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Mutant Sequence
VGINVKCKHSGQCLAPCKDAGMRFGKCINGKCDCTPK
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Sequence Length
37
Mass(Da)
3906
Sequence Removed Signal Peptide
VGINVKCKHSGQCLAPCKDAGMRFGKCINGKCDCTPK
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N.A.
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Kv1.3 IC50
0.055 nM
 .
Blocker
 [1]
References
Ref 1 Unusual binding mode of scorpion toxin BmKTX onto potassium channels relies on its distribution of acidic residues. Biochem Biophys Res Commun. 2014 Apr 25;447(1):70-6. doi: 10.1016/j.bbrc.2014.03.101. Epub 2014 Apr 3.
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