Peptide Information

General Information of This Peptide
Peptide ID
BTDP000927
Peptide Name
Toxin MeKTx13-3 (G11R,K26A,I28T,D33H)
Symonym
Toxin MeKTx13-3 (G11R,K26A,I28T,D33H)
3D Structure
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2D Sequence
3D Structure
Source
Predict by Alphafold2
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Alphafold Parameters: msa_mode: mmseqs2_uniref_env model_type: auto num_recycles: auto
Original Sequence
VGINVKCKHSGQCLKPCKDAGMRFGKCINGKCDCTPK
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Mutant Sequence
VGINVKCKHSRQCLKPCKDAGMRFGACTNGKCHCTPK
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Sequence Length
37
Mass(Da)
4015
Sequence Removed Signal Peptide
VGINVKCKHSRQCLKPCKDAGMRFGACTNGKCHCTPK
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N.A.
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Kv1.3 IC50
0.9674 nM
 .
Blocker
 [1]
References
Ref 1 Structural basis of a potent peptide inhibitor designed for Kv1.3 channel, a therapeutic target of autoimmune disease. J Biol Chem. 2008 Jul 4;283(27):19058-65. doi: 10.1074/jbc.M802054200. Epub 2008 May 14.
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