Peptide Information

General Information of This Peptide
Peptide ID
BTDP000900
Peptide Name
MgTX (K28A)
Symonym
MgTX (K28A)
3D Structure
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2D Sequence
3D Structure
Source
Predict by Alphafold2
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Alphafold Parameters: msa_mode: mmseqs2_uniref_env model_type: auto num_recycles: auto
Original Sequence
TIINVKCTSPKQCLPPCKAQFGQSAGAKCMNGKCKCYPH
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Mutant Sequence
TIINVKCTSPKQCLPPCKAQFGQSAGAACMNGKCKCYPH
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Sequence Length
39
Mass(Da)
4122
Sequence Removed Signal Peptide
TIINVKCTSPKQCLPPCKAQFGQSAGAACMNGKCKCYPH
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N.A.
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Kv1.1 Inhibition rate .
100 nM
Blocker
 [1]
 Target Info    Kv1.3 IC50
216 nM
 .
Blocker
 [1]
References
Ref 1 Recombinant expression of margatoxin and agitoxin-2 in Pichia pastoris: an efficient method for production of KV1.3 channel blockers. PLoS One. 2012;7(12):e52965. doi: 10.1371/journal.pone.0052965. Epub 2012 Dec 26.
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