Peptide Information

General Information of This Peptide
Peptide ID
BTDP000889
Peptide Name
Discrepin (R19I,D20K)
Symonym
Discrepin (R19I,D20K)
3D Structure
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2D Sequence
3D Structure
Source
Predict by Alphafold2
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Alphafold Parameters: msa_mode: mmseqs2_uniref_env model_type: auto num_recycles: auto
Original Sequence
ZIDTNVKCSGSSKCVKICIDRYNTRGAKCINGRCTCYP
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Mutant Sequence
ZIDTNVKCSGSSKCVKICIKRYNTRGAKCINGRCTCYP
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Sequence Length
38
Mass(Da)
4190
Sequence Removed Signal Peptide
ZIDTNVKCSGSSKCVKICIKRYNTRGAKCINGRCTCYP
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N.A.
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Kv11 Inhibition rate
20.2 %
2.4 μM
Blocker
 [1]
References
Ref 1 A common "hot spot" confers hERG blockade activity to alpha-scorpion toxins affecting K+ channels. Biochem Pharmacol. 2008 Sep 15;76(6):805-15. doi: 10.1016/j.bcp.2008.07.008. Epub 2008 Jul 18.
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